Weekend Wonderings

Written March 30th, 2014 by Ken

G Bruno

Welcome to this week’s edition of Weekend Wonderings. The basketball season is over for both the men’s and women’s teams, Spring football practice has begun and we are only a couple weeks away from the Spring Game. Grab whatever beverage that you need and let’s proceed.

The James/Wexner

We have a couple of items this week.

  • Here is an example of research work at the James being commercialized, via a licensing agreement, as an avenue to get their research results available for general medical treatment, as well as provide some economic benefit to Ohio State.

The Ohio State University, through the Ohio State Innovation Foundation, has signed an exclusive world-wide licensing agreement with MedVax Technologies, Inc., for the licensing of groundbreaking cancer peptide vaccine technologies.

The anticancer vaccine technologies are designed for the treatment and prevention of cancers associated with the HER2 protein. These include breast, ovarian, lung, colon and pancreatic cancers, and gastrointestinal stromal tumors. The commitment by MedVax will allow innovative clinical trials for various cancers to be conducted in the near future.

  •  Sometimes knowing what doesn’t work is very valuable, too.  The results of this study show the importance of follow-up studies done by a research university such as Ohio State. Rather than accept that an anti-cancer agent “works” and be done with it, this study points up the distinct possibility that in some patients, it may actually cause cancer growth.

Anticancer agents that target a cell-cycle regulatory protein to inhibit tumor growth might actually promote the development and progression of certain B-cell lymphomas, according to a new study led by researchers at The Ohio State University Comprehensive Cancer Center.

The study indicates that inhibiting CDK4, a regulator of the cell cycle, promotes genetic instability and the development or progression of B-cell lymphomas that are driven by the MYC oncogene.


We’re sort of between seasons with the end of the basketball season for Ohio State, and the commencement of spring football practice. Now, if we can just get through the summer. (Hint; not a problem). So, to fill my time as basketball season wound down, I explored on-line courses. My intent is to take courses on topics that personally interest me, nothing “professional” involved at all. My first foray was an online class in ‘Genetics & Evolution’.  It was interesting, educational and entertaining; I actually learned quite a bit of new “stuff”. It was time well spent for me. Next up, in a couple of weeks, is a course on ‘Science of The Solar System’. [So, Eric and Charles, if you think I can be insufferable now, just wait..]

The nice thing is that these courses, although on a schedule, can be easily managed around your schedule. It might be worth you while to check them out.

To lighten up your day, here is an article from one of my favorite non-tBBC writers, Professor PZ Myers.  Apparently,

“Gwyneth Paltrow is getting divorced, and I don’t care. I can’t say that I’ve ever even given a thought to her marital status before. But what is rather fascinatingly bizarre is her pretentious gooeyness: she calls her divorce Conscious Uncoupling…and reading elsewhere through her blog you get the impression of a young woman with so much money that she can cheerfully indulge in every poorly justified and absurd fad.”

“Conscious Uncoupling”? Any divorce that I’m aware of has been called a profound “Financial Uncoupling”. First, I suggest that you click on the PZ Myers link to read his take on the affair, then click on the above link to get a take on Conscious Uncoupling.

Sunday’s Song

From Mary McLaughlin, You Saw His Eyes.

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