Weekend Wonderings

Written November 10th, 2013 by Ken

thinking chimp

Welcome to the latest edition of Weekend Wonderings. Take a minute, grab whatever you drink on a Sunday afternoon/evening and let’s carry on. This will be a nice break from yard work for you. Besides, the Browns and the Buckeyes are off this weekend, so what else would you have planned?

The James/Wexner, Cleveland Clinic

As expected, we have a couple items this week.

First up, researchers at The James have determined, through whole-genome sequencing, that the human papillomavirus (HPV) can directly damage genes and chromosomes, thus contributing to cancer.

Published in the journal Genome Research, this laboratory study used whole-genome sequencing to investigate the relationship between the HPV and host genomes in human cancers.

“Our sequencing data showed in vivid detail that HPV can damage host-cell genes and chromosomes at sites of viral insertion,” says co-senior author David Symer, MD, PhD, assistant professor of molecular virology, immunology and medical genetics at the OSUCCC – James.

“HPV can act like a tornado hitting the genome, disrupting and rearranging nearby host-cell genes,” Symer explains. “This can lead to overexpression of cancer-causing genes in some cases, or it can disrupt protective tumor-suppressor genes in others. Both kinds of damage likely promote the development of cancer.”

“HPV can act like a tornado hitting the genome, disrupting and rearranging nearby host-cell genes,” Symer explains. “This can lead to overexpression of cancer-causing genes in some cases, or it can disrupt protective tumor-suppressor genes in others. Both kinds of damage likely promote the development of cancer.”

Read More

The Week That Were: 8.31.13

Written September 2nd, 2013 by MaliBuckeye

For those unfamiliar with this feature, consider it your cheat sheet for the conversations around the grill on Labor Day. As always, these come with a melodic interlude to play gently in the background during your perusal… because you’re that important to me.

Haircolor Brought To You By Home Depot

It was the best of times, it was the… well… best of times. Football was played, plays were made, and the long summer doldrums finally came to an end.

Sawkaralyna got us started off in style, scoring on the third play of their first possession and kicking off the annual “Hey, we’re pretty good! Oh, that’s right… we have to play  in the same conference as Alabama/Georgia/Florida/LSU… nevermind.” The only significant storyline to come out of this game, other than the fact that sometimes “new school clothes” aren’t always fashionable, is the fact that ESPN’s love-fest for all things Clowney turned into the predictable hate-fest for the sophomore after he didn’t balance the budget/solve global warming/play like a Heisman candidate. Whatever helps them get their ratings points, right?

Speaking of firsts, the news this offseason was about the new “targeting” rule and it’s potential impact on the game.  Your future trivia answer to “who was the first college player to be ejected under this rule?’ is none other than Tulane’s Lorenzo Doss. Small Ohio State related fact that’s stuck in my brain for some reason- In 1995, the NCAA decided to crack down on “showboating” and OSU’s Terry Glenn was the first person flagged after signaling “First Down” following a catch against Boston College in the Kickoff Classic.  What a cute rule that was…

At any rate, the impact (see what I did there?) of the new rule was certainly felt across the first weekend; Northwestern had a game-winning drive extended after Cal’s best pass rusher was flagged for “targeting” on a tackle in the end zone, Texas A&M lost a player for a similar infraction (although, to be honest, it was a really bad call), and Oregon had to go and “one up them” (as always) with this potentially crippling hit against Nicholls State. To be fair to the defender, though, everyone in the stadium was yelling “Duck!” to the Nicholls QB. At least that’s what I think they meant…

Another major story this weekend was the debilitating sanctions that hit Heisman winner Johnny Manziel following the “autograph” scandal. I can’t imagine what it was like for him to sit there on the sidelines for that time, missing the change to be with his teammates and… yeah, in the time it took you to read this sentence, his “suspension” was over. I wish my car had a suspension that cushy…. Read More

Guest Post- Who’s Next?

Written June 9th, 2011 by MaliBuckeye

Part two from Ty Kelly’s manifesto after winning our bowl competition; for background, allow him to reintroduce himself.

Time to spin the wheel?

Now, let’s talk about the future of the head football coaching position at The Ohio State University. Clearly, we have to look at it from the administration and the athletic director’s viewpoint – whoever that may be in seven months, (because an argument can be made that A.D. Gene Smith, and Pres. E. Gordon Gee may not last another three months at Ohio State).

Regardless, the 2012 A.D. and OSU brass will likely be looking for three main criteria-

  1. Somebody who has an impressive record of head coaching experience.
  2. A candidate with a proven record not only on the field, but a record of a clean, drama-free program.
  3. Someone with a disciplinarian personality, who can endure the pressures of  the NCAA microscope while executing his duties as CEO of one of the elite Division 1 teams in America.

So…who fit this description ?  Bo Pelini? … Probably.  Jon Gruden? … Maybe. Gary Patterson? Urban Meyer?  Each candidate has their pros and cons. I will go in to full detail for the top tier candidates as to why or why not they may be the head coach at OSU in 2012, and I will briefly go over the rest of the candidates who could be considered viable in the position.

Read More

Optimization WordPress Plugins & Solutions by W3 EDGE
Optimization WordPress Plugins & Solutions by W3 EDGE