Weekend Wonderings: Anniversary Edition

Written May 18th, 2014 by Ken

thru_looking_glassWelcome to this week’s edition of Weekend Wonderings. Grab whatever beverage that you need and let’s proceed. My Lovely Bride and I will. You can be sure of that. This coming week we’ll be taking a couple days off to celebrate our 25th wedding anniversary.  As I tell her, it’s been the best 25 (26 if you count courtship) years of my life. To no one’s surprise, we both agree on that sentiment.

The James/Wexner:

This is of some interest: researchers at the James have genetically modified immune cells (T-cells) that hunt down and kill cancer cells, multiple myeloma, in this case, themselves a product of genetic “modification”.  Below are the quick hitters.

A new study by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) provides evidence that genetically modifying immune cells might effectively treat multiple myeloma, a disease that remains incurable and will account for an estimated 24,000 new cases and 11,100 deaths in 2014.

The researchers modified a type of human immune cell – called T lymphocytes, or T cells – to target a molecule called CS1, which is found on more than 95 percent of myeloma cells, and to kill the cells. The researchers grew the modified cells in the lab to increase their numbers and then injected them into an animal model where they again killed human myeloma cells.

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