Weekend Wonderings

Written September 22nd, 2013 by Ken


Welcome to another edition of Weekend Wonderings. Take a minute, grab whatever you drink on a Sunday afternoon and let’s carry on.

Go ahead, I’ll wait.

The James/Wexner

First, by the end of the month, the James will open a Phase 2 clinical trial to test two drugs for the treatment of triple negative breast cancer – a very aggressive type of cancer with high rates of recurrence.

Triple negative breast cancer, which accounts for 15 to 20 percent of breast cancers, is so hard to treat because it doesn’t have any of the receptors (substances found inside cells that give rise to cancer) that existing drugs are able to fight…

Let’s hope that these trials come up with a solution, because if treatment drugs can’t “find” anything to latch onto, the treatment just becomes that more difficult.

dnaNext, is an article written by Sameek Roychowdhury. MD, PhD about the use of genomics in clinical trials.

 Gene sequencing technology called next-generation sequencing will enable oncologists to determine which of 200-plus significant genes are altered in a patient’s cancer and to use this information to guide therapy. Ohio State is among the leaders in the country in promoting and championing this precision oncology strategy.

I’m a believer in the use of genomics as both a diagnostic and a treatment approach . There are many “families” of cancer, such as breast, prostate, lung, etc., and several subsets within each family. This is not a one-size-fits-all disease. I’m very familiar with the subsets where there is no definitive cause; which leads to the disease likely being incurable. This genomics approach may get us over that hurdle. Read More

Is It Time To Ban Silver Bullet Points? That’s Debatable

Written May 9th, 2012 by MaliBuckeye

May’s second midweek madness gets existential. The big story of the day was the “discussion” about the future of our favorite sport- more on that after the jump.

Well, shoot.

Buckeye 411

But one thing is for sure – Urban Meyer will bring hardware back to Columbus with him before all is said and done. Gold pants, B1G titles and crystal footballs. For everyone who has piled on over the last twelve months – from those in Ann Arbor, Madison, and SEC country to those posted up at the headquarters of ESPN, Sports Illustrated and The Sporting News – there’s simply no way around it. Urban Meyer wins, and he wins big.

The benefactor? THE Ohio State University.

Read More

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