Well, the first holiday weekend of the summer is soon upon us. Memorial Day reminds us of those who gave the ultimate sacrifice, and also that there are still people who savor their Constitutional right to be wrong. Words matter, people. At any rate, today’s tune is just a little something appropriately mournful and full of the promise that fills the coming months.
Welcome to this week’s edition of Weekend Wonderings. Grab whatever beverage that you need and let’s proceed. My Lovely Bride and I will. You can be sure of that. This coming week we’ll be taking a couple days off to celebrate our 25th wedding anniversary. As I tell her, it’s been the best 25 (26 if you count courtship) years of my life. To no one’s surprise, we both agree on that sentiment.
This is of some interest: researchers at the James have genetically modified immune cells (T-cells) that hunt down and kill cancer cells, multiple myeloma, in this case, themselves a product of genetic “modification”. Below are the quick hitters.
A new study by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) provides evidence that genetically modifying immune cells might effectively treat multiple myeloma, a disease that remains incurable and will account for an estimated 24,000 new cases and 11,100 deaths in 2014.
The researchers modified a type of human immune cell – called T lymphocytes, or T cells – to target a molecule called CS1, which is found on more than 95 percent of myeloma cells, and to kill the cells. The researchers grew the modified cells in the lab to increase their numbers and then injected them into an animal model where they again killed human myeloma cells.
After the pummeling that the Aztecs took, let’s see how many of our wishes came true:
For the first time since 2005, the San Diego State Aztecs visited Columbus to play the Ohio State Buckeyes. The Aztecs failed to score until late in the 3rd quarter, falling 42-7 in a near total domination in all phases of the game. With Braxton Miller down with a minor injury, Kenny Guiton stepped up and delivered 19/27 passes for 152 yards for 2 touchdowns and 1 interception, and added 9 carries for 83 yards and a touchdown. His counterpart put up 21/34 for 207 yards, one score and one interception.
For the running game specifically, Jordan Hall ran the ball the most for the Buckeyes, who spread the ball around among their running back committee, and picked up 13 carries for 75 yards and a touchdown. Most impressively, the young defensive line held an experienced running team to 60 total running yards on 24 attempts for the day, forcing them to go away from their preferred style of play.
The Aztecs got the first shot at offense but found the going troublesome early against the OSU defense. While opportunities were present for moving the ball, SDSU wasn’t able to connect on either of their first two passes. After starting with atrocious field position, they were forced to punt the ball back to OSU, giving them the ball at the 50.
Braxton Miller, taking advantage of his Heuerman up the middle, managed to keep the first drive moving. Unfortunately, Miller suffered an MCL sprain while converting a third down close to the endzone and was kept out of the game for the remainder of the day. On the next play, Kenny Guiton tossed the ball to Dontre Wilson on an outside run to the left for the first touchdown of the young running back’s career.
Dingwell tossed a pick on the very next possession straight into the waiting arms of Doran Grant. Unfortunately Guiton wasn’t able to get the offense moving, and the Buckeyes were forced to punt despite the excellent field position. But things changed on Guiton’s second drive. He made a number of good reads on the zone read with Dontre Wilson, and delivered a huge touchdown strike to Corey Brown 27 yards down the left side of the field. Impressively, the Buckeye backup QB stood tall and took a shot while delivering the ball exactly where it needed to be.